Since the human papillomavirus (HPV) vaccine immunisation programme began in September 2008 up to
The MHRA collects information on suspected side effects to vaccines and medicines via the Yellow Card Scheme. Two HPV vaccines, Cervarix and Gardasil, are licensed for use in the UK, with Cervarix routinely used within the HPV vaccine immunisation programme.
It is important to note that Yellow Card reports relate to ‘suspicions’ that a side effect may have occurred. They may relate to true side effects, or they may be due to coincidental illness. As reports are not necessarily proof that a vaccine or medicine was a cause of the reported illness, the data cannot be used to estimate the true frequency of side effects to the vaccine. The known frequency of established side effects is listed in the available product information.
As with all vaccines and medicines, the MHRA keeps the safety of HPV vaccines under continual review. The MHRA’s detailed safety assessment of Cervarix after 4.5 million doses had been used is published at:
The benefits of HPV vaccination in protecting against cervical cancer far outweigh any known side effects.