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Clostridium

Health written question – answered on 21st January 2008.

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Photo of James Duddridge James Duddridge Opposition Whip (Commons)

To ask the Secretary of State for Health what assessment he has made of the effectiveness of organic probiotics in tablet form in reducing the risk of developing Clostridium difficile.

Photo of Ann Keen Ann Keen Parliamentary Under-Secretary (Health Services), Department of Health

There is currently insufficient clinical evidence to support the use of probiotics in any form for the prevention of Clostridium difficile infection.

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Annotations

Grace Filby
Posted on 23 Jan 2008 2:00 pm (Report this annotation)

NB: British Medical Journal:
http://www.bmj.com/cgi/content/full/335/7610/80
BMJ 2007;335:80 (14 July), doi:10.1136/bmj.39231.599815.55 (published 29 June 2007)

Please see the information box: "What this study adds"

including this point:

'The cost to prevent one case of diarrhoea was £50 (74; $100) and £60 (87.5; $120) to prevent one case of C difficile.'

Research:
Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial

The authors of the research paper are: Mary Hickson, research dietitian, Aloysius L D'Souza, research fellow, Nirmala Muthu, research nurse, Thomas R Rogers, professor of clinical microbiology and honorary consultant (Hammersmith Hospitals NHS Trust), Susan Want, clinical scientist, Chakravarthi Rajkumar, senior lecturer, Christopher J Bulpitt, professor of geriatric medicine