It is a substantial further threat. Indeed, if we shut ourselves away from Europe, we will throw away the advantage that we have in this country from our membership of the EU in terms of our future R and D. My hon. Friend is absolutely right.

This is something that we perhaps do not notice happening. It is easy to miss it, and there are not catastrophic consequences from disinvesting in R and D as far as universities and research centres are concerned, but it is potentially catastrophic for the future competitiveness of this country and the future of the sort of arrangements that I have explained exist in Southampton and have an impact in the area, the region and the country as a whole. I urge the Minister to take careful note of this debate and ensure that the investment that should be there for the future is put in place and that commitments are made to ensure that that carries on coming in to support our universities and our research activities, which are so valuable and such a source of potential fuel for this country’s ambitions across the world.